2010年8月30日星期一

A tough pill to swallow

A tough pill to swallow


When C.W. MacLeod’s cholesterol shot sky-high, the Texas businessman was only too happy to find a drug to bring it down.

For two years, the 57-year-old Houston resident dutifully took Vytorin, relying on his doctor’s assurance that as his levels of so-called "bad" cholesterol dropped, so would his risk of heart attack.

But MacLeod’s confidence was shaken this week, when he and millions of other Vytorin users learned that it and its component drug, Zetia, failed to work as widely expected. Final results of a clinical trial showed the drugs reduced LDL cholesterol, but failed to slow the buildup of artery-clogging plaque, suggesting they’ll do little or nothing to prevent heart attacks.

“It hasn’t hurt my body, but apparently it hasn’t done any good either,” said MacLeod, who wonders why he’s been shelling out $100 a month in co-payments for a brand-name drug that doesn’t work.

“If lowering your cholesterol doesn’t reduce your risk,. Please find True religion jeans online ,you will have big surpirse. then what’s the point?” another Vytorin user wrote on an msnbc.. We have many fashionable sexy lingerie have style of bunny costume.com message boardabout the issue. “Maybe I’m dense, but I just don’t understand.”

Those questions are on the minds of millions of consumers in the wake of a string of startling findings about some of the nation’s best-selling — and most heavily promoted — drugs. In less than a year, patients have learned that a popular diabetes drug, Avandia, may raise the risk of heart attack , and that antidepressants, the most widely prescribed drugs in America , may work no better than placebo.

They’ve watched as the federal Food and Drug Administration expanded use of a top cancer drug,. Large selection of women's pajamas,Glam and much more Avastin , to treat breast cancer,. Jeans will be more slim look even better, plesae choose Skinny jeans from our website. on basis of a trial that showed that while the drug slowed the disease, it didn’t impact overall survival.

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