For two years, the 57-year-old Houston resident dutifully took Vytorin, relying on his doctor’s assurance that as his levels of so-called "bad" cholesterol dropped, so would his risk of heart attack.
But MacLeod’s confidence was shaken this week, when he and millions of other Vytorin users learned that it and its component drug, Zetia, failed to work as widely expected. Final results of a clinical trial showed the drugs reduced LDL cholesterol, but failed to slow the buildup of artery-clogging plaque, suggesting they’ll do little or nothing to prevent heart attacks.
“It hasn’t hurt my body, but apparently it hasn’t done any good either,” said MacLeod, who wonders why he’s been shelling out $100 a month in co-payments for a brand-name drug that doesn’t work.
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